Crisis Management and planning based on critical issues as rescue and emergency evacuation in urban land uses is very important. This approach in Isfahan is necessary. Concentration of heritage land uses in central area of Isfahan along with Factors such as inadequate access, narrow streets and alleys, spatial incompatibility, structural maladaptation, gradual erosion of the building and lack of systematic planning in heritage spaces has been caused the historical land uses of Isfahan to be vulnerable in potential disaster. Method of research in the paper is descriptive and analysis- survey and its type is fundamental and practice. The research with emphasis on field work, check list and AHP model is trying to analysis of vulnerability of heritage land uses and their prioritization in emergency evacuation. Structure of research has been established on Basic Indicators, Management criteria. The case study is 420 heritage building of Isfahan the documented in national list. Results that showed Isfahan third district is very vulnerable and in the first priority of evacuation and rescue based on 0.49 weight in basic indicators and 0.53 weight in management ones. First, fifth, sixth and other urban district of Isfahan are in next stages. Identification and classification of monument based on degree and severity of destruction, reinforcement of buildings, training of evacuation operations and civil defense in land use are major strategies in disaster management of these land uses.